Wednesday, December, 07,2022

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Reversal of Type 2 Diabetes Mellitus- A New Concept

Treating diabetes is an art, in addition to aiming at controlling sugar values & preventing complications now REVERSAL OF DIABETES is a new concept.

Reversing diabetes is a term that usually refers to a significant long-term good sugar control in people with type 2 diabetes.

People with type 2 diabetes that are able to get their HbA1c below 6 gm% without taking diabetes medication are said to have reversed or resolved their diabetes.

Although there’s no cure for type 2 diabetes, however, it’s possible for some people to reverse it. Through diet changes and weight loss, the patient may be able to reach and hold normal blood sugar levels without medication. The key to reversing diabetes seems to be weight loss.

Sometimes losing enough weight could help to live diabetes-free; especially if a patient had the disease for a few years and haven’t needed insulin.

With time and dedication, type 2 diabetes can be reversed and the results can be very rewarding, with less tiredness and better all-round health.

Research indicates that effective ways to reverse diabetes include:  Low-carbohydrate diet  Very low-calorie diets

  •  Exercise
  •  Bariatric surgery
  •  Fasting

In type 2 diabetes there is insulin resistance as compared to insulin deficiency. Insulin resistance is responsible for hyperglycemia.

In a normal person, insulin increases the uptake of carbohydrates in the liver, muscles, and other target organs. In obese person as a consequence of high visceral and subcutaneous fat deposition, insulin does not work efficiently at the target site to lower blood levels of glucose.

The key point for reversal of diabetes is to reduce this visceral and subcutaneous fat by a low-calorie diet, exercise, bariatric surgery, fasting etc.


Low-carbohydrate diets are known for lowering the amount of insulin the body needs to produce, resulting in less insulin resistance.

A study showed that a low-carbohydrate Mediterranean diet was able to achieve significant rates of remission in people with type 2 diabetes.

High blood sugar levels destroy the insulin-secreting pancreatic beta cells which further aggravate hyperglycaemia. 


Very-low-calorie diets (VLCD) have been shown to achieve significant weight loss, reduce insulin resistance and allow people with type 2 diabetes to come off their diabetes medication.

A study showed that an 8-week 800 kcal per day diet was able to achieve remission from diabetes in nearly 65% of patients with type 2 diabetes.

The reversal of diabetes appeared to be correlated with significant reductions in fat storage within the liver and pancreas.

A VLCD is regarded as an extreme form of diet and therefore should be undertaken with care. This type of diet is extreme.

It means working with a professional and being very controlled with how many calories be eaten by the patient. But the chance that it could send into remission may give a strong motivation to stick to it. It’s important to get started on a weight-loss plan as soon as diagnosed.

EXERCISE More physical activity is a way to improve diabetes, but it may be tough to lose enough weight to go into remission with workouts alone

A modest, lowercalorie diet plus a big stepup in burning calories could put on the path to remission.

A study showed that people aim for 10,000 steps a day and at least 2 1/2 hours of moderate exercise a week along with cutting 500-750 calories a day and following specific insulin and medication routine saw more than half of them reach near-normal blood sugar without medication.

It’s the weight loss that really matters. Exercise can help to get there but expect to change the diet as well.


This type of surgery helps to lose weight by changing the stomach and digestive system to limit how much the patient can eat.

Aside from helping to lose weight, it may help reverse diabetes in other ways, although scientists don’t yet know exactly why. One theory is that it affects the hormones in the gut to help control blood glucose.

The efficacy of type 2 diabetes reversal depends on the choice of procedure, there is unilateral improvement in glycemia following the operation, and bariatric surgery has been found to be superior to intensive type 2 diabetes medical management.

Researchers estimate that upwards of three-quarters of people see their diabetes reversed after bariatric surgery.

Gastric bypass and gastric sleeve surgery have better long-term results than gastric banding. Bariatric surgery is generally an option only when BMI is 35 or higher.

FASTING Fasting can be a practical way to lose weight because it’s fairly straightforward, but it’s not a mainstream treatment for type 2 diabetes.

A very small study found that therapeutic fasting without food for a set amount of time can help reverse type 2 diabetes.

Another study showed that eating very few calories (500-600) 2 days a week and a normal diet the other days helped people with type 2 diabetes lose weight and lower their blood sugar levels.


When it comes to reversing diabetes, there’s no magic pill. If you see a product that claims to cure diabetes or replace your prescribed diabetes medication, beware.

The FDA cautions that many illegally marketed things are unproven and possibly dangerous, including:

  •  Dietary supplement
  •  Over-the-counter drugs
  •  Alternative medicines
  •  Homeopathic products
  •  Prescription drugs

Additional evidence has become available in recent years suggesting that diabetes reversal is a possible alternative to consider in place of traditional diabetes treatment and management. Hence weight reduction & maintaining ideal BMI are the key features of

REVERSAL OF DIABETES coupled up with a high fibre diet and regular physical activity.  

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